KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM12
All Species:
22.42
Human Site:
T745
Identified Species:
49.33
UniProt:
O43184
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43184
NP_003465.3
909
99542
T745
L
F
T
N
K
K
T
T
I
E
K
L
R
C
V
Chimpanzee
Pan troglodytes
XP_508106
914
100282
T750
L
F
T
N
K
K
T
T
I
E
K
L
R
C
V
Rhesus Macaque
Macaca mulatta
XP_001087980
909
99411
T745
L
F
T
N
K
K
T
T
I
E
K
L
R
C
V
Dog
Lupus familis
XP_546274
909
99674
L729
G
Q
L
K
P
L
A
L
P
S
K
L
R
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61824
903
98582
T743
L
F
T
H
K
K
T
T
M
E
K
L
R
C
V
Rat
Rattus norvegicus
Q9QYV0
816
88034
S671
H
G
H
G
V
C
D
S
S
R
H
C
H
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
S677
L
K
T
P
A
L
P
S
K
W
R
Q
P
F
R
Chicken
Gallus gallus
NP_001136322
922
101009
T757
L
F
T
S
K
K
T
T
I
E
K
L
R
S
V
Frog
Xenopus laevis
O42596
935
104143
E766
G
Y
K
N
Y
R
R
E
R
Q
I
P
Q
G
D
Zebra Danio
Brachydanio rerio
XP_001921148
773
83366
T631
H
T
A
A
S
P
Q
T
A
S
I
Y
Q
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999635
1023
111059
T752
V
S
K
S
K
G
T
T
K
Q
T
Y
P
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
43.7
N.A.
80.3
35.5
N.A.
43.3
71.5
28.3
56.7
N.A.
N.A.
N.A.
N.A.
35.8
Protein Similarity:
100
95.9
97.1
59.4
N.A.
88.1
50.3
N.A.
58
82.4
44.4
65.2
N.A.
N.A.
N.A.
N.A.
51.2
P-Site Identity:
100
100
100
20
N.A.
86.6
6.6
N.A.
13.3
86.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
20
N.A.
100
13.3
N.A.
26.6
93.3
33.3
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
0
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
10
0
46
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
19
% D
% Glu:
0
0
0
0
0
0
0
10
0
46
0
0
0
0
0
% E
% Phe:
0
46
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
19
10
0
10
0
10
0
0
0
0
0
0
0
10
0
% G
% His:
19
0
10
10
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
37
0
19
0
0
0
0
% I
% Lys:
0
10
19
10
55
46
0
0
19
0
55
0
0
0
0
% K
% Leu:
55
0
10
0
0
19
0
10
0
0
0
55
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
37
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
10
10
0
10
0
0
10
19
10
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
19
0
10
19
10
10
% Q
% Arg:
0
0
0
0
0
10
10
0
10
10
10
0
55
0
10
% R
% Ser:
0
10
0
19
10
0
0
19
10
19
0
0
0
19
10
% S
% Thr:
0
10
55
0
0
0
55
64
0
0
10
0
0
0
0
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _